The results and findings can be replicated by other researchers if they follow our method section. Any researcher can subscribe to Lifelines and work on the dataset on which we are working. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: Data are from Lifeline ( ). Received: DecemAccepted: ApPublished: May 31, 2019Ĭopyright: © 2019 Masih et al. PLoS ONE 14(5):Įditor: Fulvio D’Acquisto, University of Roehampton - Whitelands College, UNITED KINGDOM The findings allow us to better understand mood groups, especially the hedonic and anhedonic groups, and open up new avenues for intervention.Ĭitation: Masih J, Belschak F, Verbeke JMIW (2019) Mood configurations and their relationship to immune system responses: Exploring the relationship between moods, immune system responses, thyroid hormones, and social support. These differences were most significant in the hedonic and anhedonic groups. We also found that T3 and T4 levels differ significantly across all mood groups and work in very close association with lymphocytes to activate the adaptive immune system. However, in the adaptive immune system we found mean lymphocyte cell counts to be different in all four mood groups. We found significant differences between mood groups and mean cell counts for basophilic granulocytes and thrombocytes but not for monocytes, eosinophil granulocytes and neutrophil granulocytes in the innate immune system. We focus further on (3) thyroid cells: T3 and T4 and (4) on social support. Moods were measured on the positive (PA) and negative (NA) dimensions of the PANAS scale, divided in four groups based on their PA and NA median scores: hedonic, positive mood, negative mood and anhedonic. We focus (1) on the innate immune system cell count: monocytes, eosinophil granulocytes, basophilic granulocytes, neutrophil granulocytes and thrombocytes and (2) on the adaptive immune system cell count: lymphocytes (T, B and NK cells). Analyzing data on 2,057 healthy subjects in the Dutch Lifelines database we explore the relationship between immune system responses, thyroid hormone functioning and people’s mood that is expected to be moderated by social support.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |